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Cover
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OFC
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Masthead
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IFC
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Editorial Board
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i
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Topics
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ii
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Contents
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iii
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Introduction
This issue is the second part of the two issues on bone marrow disorders. As mentioned in the Introduction to Part I (Bone Marrow Disorders: Recent Advances, Part I), a lot of hard work and many hours...
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Emina E. Torlakovic,
Anna Porwit,
Jagdish Butany
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1
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Beyond the 2008 World Health Organization classification: the role of the hematopathology laboratory in the diagnosis and management of acute lymphoblastic leukemia
The diagnosis of acute lymphoblastic leukemia (ALL) is made by evaluating morphology and immunophenotype. However, appropriate risk stratification and decisions regarding the intensity of therapy are ...
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Stephanie McGregor,
Jennifer McNeer,
Sandeep Gurbuxani
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2-11
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Acute leukemias of ambiguous lineage
The 2008 edition of the WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues recognizes a special category called “leukemias of ambiguous lineage.” The vast majority of these rare leuke...
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Marie C. Béné,
Anna Porwit
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12-18
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Mastocytosis and related disorders
Mastocytosis represents a heterogeneous group of disorders characterized by an abnormal accumulation of mast cells in one or more organ systems. Mastocytosis is further divided into different subtypes...
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April Chiu,
Attilio Orazi
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19-30
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Approach to peripheral blood film assessment for pathologists
In today's age of advanced technology used in the diagnosis of many medical problems, the blood film stands out as an inexpensive and quick diagnostic tool that can generally be performed in most labo...
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David Barth
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31-48
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Pathology of sickle cell disease
Sickle cell disease (SCD) is a hereditary chronic hemolytic anemia with numerous clinical consequences. Intravascular sickling of red blood cells leads to multiorgan dysfunction. Although the pathophy...
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Janet I. Malowany,
Jagdish Butany
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49-55
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