Primary cutaneous lymphomas: a reprisal

Pileri, Alessandro; Patrizi, Annalisa; Agostinelli, Claudio; Neri, Iria; Sabattini, Elena; Bacci, Francesco; Piccaluga, Pier Paolo; Pimpinelli, Nicola; Pileri, Stefano A.

doi:10.1053/j.semdp.2011.04.002

« Previous Next »Seminars in Diagnostic Pathology
Volume 28, Issue 3 , Pages 214-233, August 2011

Primary cutaneous lymphomas: a reprisal

Alessandro Pileri Jr, MD
- Department of Internal Medicine, Geriatrics, and Nephrology, Division of Dermatology, University of Bologna, Bologna, Italy
- Address reprint requests and correspondence: Alessandro Pileri Jr, MD, Department of Internal Medicine, Geriatrics, and Nephrology, Division of Dermatology, University of Bologna, Via Massarenti 1, 40138 Bologna, Italy
Annalisa Patrizi, MD
- Department of Internal Medicine, Geriatrics, and Nephrology, Division of Dermatology, University of Bologna, Bologna, Italy
Claudio Agostinelli, MD, PhD
- Department of Haematology and Oncological Sciences “L. and A. Seràgnoli,” Bologna University School of Medicine, Bologna, Italy
Iria Neri, MD
- Department of Internal Medicine, Geriatrics, and Nephrology, Division of Dermatology, University of Bologna, Bologna, Italy
Elena Sabattini, MD
- Department of Haematology and Oncological Sciences “L. and A. Seràgnoli,” Bologna University School of Medicine, Bologna, Italy
Francesco Bacci, MD
- Department of Haematology and Oncological Sciences “L. and A. Seràgnoli,” Bologna University School of Medicine, Bologna, Italy
Pier Paolo Piccaluga, MD, PhD
- Department of Haematology and Oncological Sciences “L. and A. Seràgnoli,” Bologna University School of Medicine, Bologna, Italy
Nicola Pimpinelli, MD
- Department of Critical Care, Medicine and Surgery, Section of Dermatology, University of Florence, Florence, Italy
Stefano A. Pileri, MD
- Department of Haematology and Oncological Sciences “L. and A. Seràgnoli,” Bologna University School of Medicine, Bologna, Italy

Primary cutaneous lymphomas (PCLs) are a group of lymphoid neoplasms provided with heterogeneous clinical, histological, immunohistochemical and molecular features. They can be classified in two groups: cutaneous T-cell lymphomas (CTCLs) and cutaneous B-cell lymphomas (CBCLs). Recent studies show an increase of the incidence of PCLs over the last three decades. Our aim is to evaluate the commonest types of PCL analysing the clinical characteristics, histology, phenotype, molecular biology, prognosis and therapy.

Keywords: Primary cutaneous lymphomas, Clinical characteristics, Histology, Immunohistochemistry, Molecular biology