Seminars in Diagnostic Pathology
Volume 27, Issue 1 , Pages 5-12, February 2010

Epitheliosis, infiltrating epitheliosis, and radial scar

  • Vincenzo Eusebi, MD, FRCPath

      Affiliations

    • Corresponding Author InformationAddress reprint requests and correspondence: Vincenzo Eusebi, MD, FRCPath, Sezione Anatomia Patologica, Ospedale Bellaria, Via Altura 3, 40139 Bologna, Italy
    • ,
  • Rosemary R. Millis, MB, BS, FRCPath, DSc(Med)

Department of Pathology “M. Malpighi,” Bellaria Hospital, University of Bologna, Bologna, Italy

The lesion termed “infiltrating epitheliosis” (IE) by Azzopardi is described using his original criteria. The differential diagnosis from radial scar (RS) is discussed. It appears that IE and RS are histologically and histogenetically different and are also associated with a different risk of carcinoma. IE can be associated with either in situ or invasive carcinoma, whereas RS being more like a process of involution is very seldom involved by a carcinoma. Therefore, whatever name is used among the several found in the literature, it should be made clear they are not interchangeable when reporting on lesions like IE and RS.

Keywords: Infiltrating epitheliosis, Radial scar

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PII: S0740-2570(09)00098-7

doi:10.1053/j.semdp.2009.12.008

Seminars in Diagnostic Pathology
Volume 27, Issue 1 , Pages 5-12, February 2010

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