Seminars in Diagnostic Pathology
Volume 26, Issue 3 , Pages 141-149 , August 2009

Postradiation cutaneous vascular tumors of the breast: a review

  • Joshua Weaver, MD

      Affiliations

    • Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio
    • ,
  • Steven D. Billings, MD

      Affiliations

    • Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio
    • Department of Dermatology, Cleveland Clinic, Cleveland, Ohio
    • Corresponding Author InformationAddress for correspondence: Steven D. Billings, MD, Department of Anatomic Pathology/L25, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195

References 

  1. Morgan MB, Swann M, Somach S, et al. Cutaneous angiosarcoma: A case series with prognostic correlation. J Am Acad Dermatol. 2004;50:867–874
  2. Stewart FW, Treves N. Lymphangiosarcoma in postmastectomy lymphedema; a report of six cases in elephantiasis chirurgica. Cancer. 1948;1:64–81
  3. Hallel-Halevy D, Yerushalmi J, Grunwald MH, et al. Stewart-Treves syndrome in a patient with elephantiasis. J Am Acad Dermatol. 1999;41:349–350
  4. Shehan JM, Ahmed I. Angiosarcoma arising in a lymphedematous abdominal pannus with histologic features reminiscent of Kaposi's sarcoma: Report of a case and review of the literature. Int J Dermatol. 2006;45:499–503
  5. Strobbe LJ, Peterse HL, van Tinteren H, et al. Angiosarcoma of the breast after conservation therapy for invasive cancer, the incidence and outcome (An unforseen sequela). Breast Cancer Res Treat. 1998;47:101–109
  6. Cozen W, Bernstein L, Wang F, et al. The risk of angiosarcoma following primary breast cancer. Br J Cancer. 1999;81:532–536
  7. Brenn T, Fletcher CD. Radiation-associated cutaneous atypical vascular lesions and angiosarcoma: Clinicopathologic analysis of 42 cases. Am J Surg Pathol. 2005;29:983–996
  8. Billings SD, McKenney JK, Folpe AL, et al. Cutaneous angiosarcoma following breast-conserving surgery and radiation: An analysis of 27 cases. Am J Surg Pathol. 2004;28:781–788
  9. Di Tommaso L, Rosai J. The capillary lobule: A deceptively benign feature of post-radiation angiosarcoma of the skin: Report of three cases. Am J Dermatopathol. 2005;27:301–305
  10. Deyrup AT, McKenney JK, Tighiouart M, et al. Sporadic cutaneous angiosarcomas: A proposal for risk stratification based on 69 cases. Am J Surg Pathol. 2008;32:72–77
  11. Nascimento AF, Raut CP, Fletcher CD. Primary angiosarcoma of the breast: Clinicopathologic analysis of 49 cases, suggesting that grade is not prognostic. Am J Surg Pathol. 2008;32:1896–1904
  12. Maddox JC, Evans HL. Angiosarcoma of skin and soft tissue: A study of forty-four cases. Cancer. 1981;48:1907–1921
  13. Requena L, Kutzner H, Mentzel T, et al. Benign vascular proliferations in irradiated skin. Am J Surg Pathol. 2002;26:328–337
  14. Diaz-Cascajo C, Borghi S, Weyers W, et al. Benign lymphangiomatous papules of the skin following radiotherapy: A report of five new cases and review of the literature. Histopathology. 1999;35:319–327
  15. Rosso R, Gianelli U, Carnevali L. Acquired progressive lymphangioma of the skin following radiotherapy for breast carcinoma. J Cutan Pathol. 1995;22:164–167
  16. Celis AV, Gaughf CN, Sangueza OP, et al. Acquired lymphangiectasis. South Med J. 1999;92:69–72
  17. Jappe U, Zimmermann T, Kahle B, et al. Lymphangioma circumscriptum of the vulva following surgical and radiological therapy of cervical cancer. Sex Transm Dis. 2002;29:533–535
  18. Gengler C, Coindre JM, Leroux A, et al. Vascular proliferations of the skin after radiation therapy for breast cancer: Clinicopathologic analysis of a series in favor of a benign process: A study from the French Sarcoma Group. Cancer. 2007;109:1584–1598
  19. Patton KT, Deyrup AT, Weiss SW. Atypical vascular lesions after surgery and radiation of the breast: A clinicopathologic study of 32 cases analyzing histologic heterogeneity and association with angiosarcoma. Am J Surg Pathol. 2008;32:943–950
  20. Mattoch IW, Robbins JB, Kempson RL, et al. Post-radiotherapy vascular proliferations in mammary skin: A clinicopathologic study of 11 cases. J Am Acad Dermatol. 2007;57:126–133
  21. Fineberg S, Rosen PP. Cutaneous angiosarcoma and atypical vascular lesions of the skin and breast after radiation therapy for breast carcinoma. Am J Clin Pathol. 1994;102:757–763

PII: S0740-2570(09)00047-1

doi: 10.1053/j.semdp.2009.10.001

Seminars in Diagnostic Pathology
Volume 26, Issue 3 , Pages 141-149 , August 2009

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