Seminars in Diagnostic Pathology
Volume 26, Issue 3 , Pages 131-140, August 2009

Cutaneous CD30 lymphoproliferative disorders and similar conditions: a clinical and pathologic prospective on a complex issue

  • Joan Guitart, MD

      Affiliations

    • Cutaneous Lymphoma Clinic and Dermatopathology Laboratory, Northwestern University, Feinberg Medical School, Chicago, Illinois
    • Corresponding Author InformationAddress for correspondence: Joan Guitart, MD, Department of Dermatology, Northwestern University, Feinberg Medical School, 676 North Saint Clair, Suite 1600, Chicago, IL 60611
  • ,
  • Christiane Querfeld, MD

      Affiliations

    • University of Chicago, Section of Dermatology, Chicago, Illinois

We elaborate on the diagnosis of CD30 positive cutaneous lymphoproliferative conditions including the various clinical and pathological presentations, our understanding of its pathomechanisms and prognostic implications. The most common reactive conditions that can simulate CD30 lymphoproliferative conditions, including arthropod bite reactions, various viral infections, pityriasis lichenoides and lymphocytic papules in myelodysplastic syndrome, are discussed in detail.

Keywords: Lymphomatoid papulosis, CD30, Pseudolymphoma, Anaplastic large cell lymphoma

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PII: S0740-2570(09)00020-3

doi:10.1053/j.semdp.2009.09.001

Seminars in Diagnostic Pathology
Volume 26, Issue 3 , Pages 131-140, August 2009