Seminars in Diagnostic Pathology
Volume 26, Issue 1 , Pages 7-9 , February 2009

Hepatotoxicity in an infant following supratherapeutic dosing of acetaminophen for twenty-four hours

  • Arthur Kubic, PharmD, CSPI

      Affiliations

    • Illinois Poison Center, Chicago, Illinois
    • Corresponding Author InformationAddress reprint requests and correspondence: Arthur Kubic, PharmD, CSPI, Illinois Poison Center, 222 South Riverside Plaza, Suite 1900, Chicago, IL 60606
    • ,
  • Anthony M. Burda, BS, Pharm, DABAT

      Affiliations

    • Illinois Poison Center, Chicago, Illinois
    • ,
  • Elizabeth Bockewitz, MD

      Affiliations

    • Illinois Poison Center, Chicago, Illinois
    • ,
  • Michael Wahl, MD, FACEP

      Affiliations

    • University of Illinois College of Medicine, Peoria, Illinois

References 

  1. Bronstein AC, Spyker DA, Cantilena LR, et al. 2006 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS). Clin Toxicol (Phila). 2007;45:815–917
  2. Erickson TB, Ahrens WR, Aks S, et al. Pediatric Toxicology: Diagnosis and Management of the Poisoned Child. New York, NY: McGraw Hill; 2004;
  3. Rudolph C, Rudolph A, Hostetter M, et al. Rudolph's Pediatrics. (ed 21). New York, NY: McGraw Hill; 2003;
  4. Flomenbaum N, Goldfrank L, Hoffman R, et al. Goldfrank's Toxicologic Emergencies. (ed 8). New York, NY: McGraw Hill; 2006;
  5. Dart RC, Erdman AR, Olson KR, et al. Acetaminophen poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol. 2006;44:1–18
  6. Micromedex® Health Care Series. Greenwood Village, CO, Thomson Health Care (edition expires 12/2008)
  7. Woo OF, Mueller PD, Olson KR, et al. Shorter duration of oral N-acetylcysteine therapy for acute acetaminophen overdose. Ann Emerg Med. 2000;35:363–368
  8. Acetadote™ (package insert). Nashville, TN: Cumberland Pharmaceuticals; 2006;
  9. Daly FF, O'Malley GF, Heard K, et al. Prospective evaluation of repeated supratherapeutic acetaminophen (paracetamol) ingestion. Ann Emerg Med. 2004;44:393–398

PII: S0740-2570(08)00121-4

doi: 10.1053/j.semdp.2008.12.010

Seminars in Diagnostic Pathology
Volume 26, Issue 1 , Pages 7-9 , February 2009

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