Seminars in Diagnostic Pathology
Volume 25, Issue 4 , Pages 317-322, November 2008

Biobanking: old activity or young discipline?

  • Manuel M. Morente

      Affiliations

    • Tumor Bank Unit, Molecular Pathology Programme, Spanish National Cancer Center, Madrid, Spain
    • Tumor Bank Unit, Molecular Pathology Programme, Cancer Research Center-IBMCC, University of Salamanca–CSIC, Salamanca, Spain
    • Corresponding Author InformationAddress reprint requests and correspondence: Manuel M. Morente, Tumor Bank Unit, Spanish National Cancer Center, CNIO, Melchor Fernández Almagro, 3, ES–28029 Madrid, Spain
  • ,
  • Pedro L. Fernández

      Affiliations

    • Tumor Bank Unit, Department of Pathology, Hospital Clinic and IDIBAPS, University of Barcelona, Barcelona, Spain
    • Tumor Bank Unit, Molecular Pathology Programme, Cancer Research Center-IBMCC, University of Salamanca–CSIC, Salamanca, Spain
  • ,
  • Enrique de Alava, PhD, MD

      Affiliations

    • Tumor Bank Unit, Molecular Pathology Programme, Spanish National Cancer Center, Madrid, Spain
    • Tumor Bank Unit, Molecular Pathology Programme, Cancer Research Center-IBMCC, University of Salamanca–CSIC, Salamanca, Spain

Biobanking is a new concept with solid bases in traditional pathology, the development of which is mandatory to allow effective translational research to flourish. Biobank activity is developing as a progressively complex young discipline playing a central role in biomedical research. This review analyzes the role of disease-driven biobanks in translational research, focusing on some aspects considered to be crucial for the future development of these institutions and service providers, including dedicated designs, funding, personnel, and ethical and legal frameworks, which, coupled with networked functioning, can provide an endless source of samples and, ideally, associated clinical information for biomedical research.

Keywords: Biobank, Biorepository, Tumor bank, Translational research

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PII: S0740-2570(08)00061-0

doi:10.1053/j.semdp.2008.07.007

Seminars in Diagnostic Pathology
Volume 25, Issue 4 , Pages 317-322, November 2008