Seminars in Diagnostic Pathology
Volume 25, Issue 1 , Pages 17-19 , February 2008

Cardiac fibromas

  • Avrum I. Gotlieb, MDCM, FRCPC

      Affiliations

    • Corresponding Author InformationAddress reprint requests and correspondence: Avrum I. Gotlieb, MDCM, FRCPC, Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Banting Institute, 100 College Street, Toronto, M5G 1L5, Ontario, Canada.

References 

  1. Chan HS, Sonley MJ, Moes CA, et al. Primary and secondary tumors of childhood involving the heart, pericardium, and great vessels (A report of 75 cases and review of the literature). Cancer. 1985;56:825–836
  2. Burke AP, Rosado-de-Christenson M, Templeton PA, et al. Cardiac fibroma: clinicopathologic correlations and surgical treatment. J Thorac Cardiovasc Surg. 1994;108:862–870
  3. Beghetti M, Gow RM, Haney I, et al. Pediatric primary benign cardiac tumors: a 15-year review. Am Heart J. 1997;134:1107–1114
  4. Becker AE. Primary heart tumors in the pediatric age group: a review of salient pathologic features relevant for clinicians. Pediatr Cardiol. 2000;21:317–323
  5. Vander Salm TJ. Unusual primary tumors of the heart. Semin Thorac Cardiovasc Surg. 2000;12:89–100
  6. De Montpreville V, Nottin R, Dulmet E, et al. Heart tumors in children and adults: clinicopathological study of 59 patients from a surgical center. Cardiovascular Pathol. 2007;16:22–28
  7. Molina JE, Edwards JE, Ward HB. Primary cardiac tumors: experience at the University of Minnesota. Thorac Cardiovasc Surg. 1990;2:183–191
  8. Turi GK, Albala A, Fenoglio JJ. Cardiac fibromatosis: an ultrastructural study. Hum Pathol. 1980;11:577–580
  9. De Montpreville VT, Serraf A, Aznag H, et al. Fibroma and inflammatory myofibroblastic tumor of the heart. Ann Diag Pathol. 2001;5:335–342
  10. Scanlan D, Radio SJ, Nelson M, et al. Loss of the PTCHI gene locus in cardiac fibroma. Cardiovascular Pathol. 2008;17:(in press)
  11. Iqbal MB, Stavri G, Mittal T, et al. A calcified cardiac mass. Int J Cardiol. 2007;115:e126–e128
  12. Ottavini G, Rossi L, Ramos SG, et al. Pathology of the heart and conduction system in a case of sudden death due to cardiac fibroma in a 6-month-old child. Cardiovasc Pathol. 1999;8:109–112
  13. Massin MM, Bricteux G, Tabache M. Giant cardiac fibroma in an asymptomatic neonate. Clin Cardiol. 1999;22:750
  14. Nakazawa S, Yamazaki Y, Yokosawa T, et al. Successful resection of cardiac fibroma with ventricular tachycardia. J Cardiovasc Surg. 1989;30:44–46
  15. Wong JA, Fishbein MC. Cardiac fibroma resulting in fatal ventricular arrhythmia. Circulation. 2000;101:E168–E170
  16. Parmley LF, Salley RK, Williams JP, et al. The clinical spectrum of cardiac fibroma with diagnostic and surgical considerations: noninvasive imaging enhances management. Ann Thorac Surg. 1988;45:455–465
  17. Mohammed W, Murphy A. Cardiac fibroma presenting as sudden death in a six-month-old infant. West Indian Med J. 1997;46:28–29
  18. Meissner C, Minnasch P, Gafumbegete E, et al. Sudden unexpected Infant death due to fibroma of the heart. J Forensic Sci. 2000;45:731–733
  19. Bapat VN, Varma GG, Hordikar AA, et al. Right-ventricular fibroma presenting as tricuspid stenosis: a case report. Thorac Cardiovasc Surg. 1996;44:152–154
  20. Pauliks LB, Miller S, Banerjee A. Intracardiac fibroma in nevoid-basal cell carcinoma (gorlin) syndrome: tissue characterization by strain rate imaging. Echocardiography. 2006;23:79–80
  21. Gonen R, Degani S, Samberg I, et al. Congenital cardiac fibroma associated with fetal arrhythmia. 1983;21:3943
  22. Efthymiou C, Abu-Omar Y, Ratnatunga C. Massive intrapericardial fibroma presenting with palpitations. Heart. 2007;93:106
  23. Bossert T, Gummert JF, Battellini R, et al. Surgical experiences with 77 primary cardiac tumors. Interact Cardiovasc Thorac Surg. 2005;4:311–315
  24. Cho JM, Danielson GK, Puga FJ, et al. Surgical resection of ventricular cardiac fibromas: early and late results. Ann Thorac Surg. 2003;76:1929–1934
  25. Piazza N, Chughtai T, Toledano K, et al. Primary cardiac tumours: eighteen years of surgical experience on 21 patients. Can J Cardiol. 2004;20:1443–1448
  26. Williams DB, Danielson GK, McGoon DC, et al. Cardiac fibroma: long-term survival after excision. J Thorac Cardiovasc Surg. 1982;84:230–236
  27. Yamaguchi M, Hosokawa Y, Ohashi H, et al. Cardiac fibroma (Long-term fate after excision). J Thorac Cardiovasc Surg. 1992;103:140–145
  28. Beghetti M, Haney I, Williams WG, et al. Massive right ventricular fibroma treated with partial resection and a cavopulmonary shunt. Ann Thorac Surg. 1996;62:882–884
  29. Valente M, Cocco P, Thiene G, et al. Cardiac fibroma and heart transplantation. J Thorac Cardiovasc Surg. 1993;106:1208–1212
  30. Sharma K, Rohlicek C, Cecere R, et al. Malignant arrhythmias secondary to cardiac requiring transplantation in a teenager. J Heart Lung Transplant. 2007;26:639–641
  31. Grolin RJ, Goltz RW. Multiple nevoid basal-cell epithelioma, jaw cysts and bifid ribs: a syndrome. N Engl J Med. 1960;262:908–912
  32. Evans DG, Ladusans EJ, Rimmer S, et al. Complications of the naevoid basal cell carcinoma syndrome: results of a population based study. J Med Genet. 1993;30:460–464
  33. Ferguson HL, Hawkins EP, Cooley LD. Infant cardiac fibroma with clonal t(1;9)(q32;q22) and review of benign fibrous tissue cytogenetics. Cancer Genet Cytogenet. 1996;87:34–37
  34. Viswanathan S, Gibbs JL, Roberts P. Clonal translocation in a cardiac fibroma presenting with incessant ventricular tachycardia in childhood. Cardiol Young. 2003;13:101–102
  35. Bossert T, Wather T, Vondrgs D, et al. Cardiac fibroma as an inherited manifestation of nevoid basal-cell carcinoma syndrome. Tex Heart Inst J. 2006;33:88–90
  36. Marci M, Ziino O, D’Angelo P, et al. Fibroma of the left ventricle in a patient with Sotos syndrome. Echocardiography. 2001;18:171–173
  37. Dehner LP. The enigmatic inflammatory pseudotumours: The current state of our understanding, or misunderstanding. J Pathol. 2000;192:277–279
  38. Coffin CM, Watterson J, Priest JR. Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor) (A clinicopathologic and immunohistochemical study of 84 cases). Am J Surg Pathol. 1995;19:859–872
  39. Burke A, Li L, Kling E, et al. Cardiac inflammatory myofibroblastic tumor: a “benign” neoplasm that may result in syncope, myocardial infarction, and sudden death. Am J Surg Pathol. 2007;31:1115–1122
  40. Rose AG, McCormick S, Cooper K, et al. Inflammatory pseudotumor (plasma cell granuloma) of the heart (Report of two cases and literature review). Arch Pathol Lab Med. 1996;120:549–554
  41. Van Beek EJ, Stolpen AH, Khanna G, et al. CT and MRI of pericardial and cardiac neoplastic disease. Cancer Imaging. 2007;7:19–26

PII: S0740-2570(07)00132-3

doi: 10.1053/j.semdp.2007.12.002

Seminars in Diagnostic Pathology
Volume 25, Issue 1 , Pages 17-19 , February 2008

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