Seminars in Diagnostic Pathology
Volume 25, Issue 1 , Pages 20-28 , February 2008

Benign cardiac tumors of the pluripotent mesenchyme

  • Pradeep Vaideeswar, MD

      Affiliations

    • Department of Pathology (Cardiovascular & Thoracic Division), Seth G. S. Medical College, Mumbai, India
    • Corresponding Author InformationAddress reprint requests and correspondence: Pradeep Vaideeswar, MD, Department of Pathology (Cardiovascular & Thoracic Division), Seth G. S. Medical College, Parel, Mumbai 400 012, India.
    • ,
  • Jagdish W. Butany, MBBS, MS, FRCPC

      Affiliations

    • Department of Pathology, Toronto General Hospital/University Health Network, Toronto, Ontario, Canada
    • Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

References 

  1. Reynen K. Cardiac myxomas. N Engl J Med. 1995;333:1610–1617
  2. Acebo E, Val-Bernal F, Gomez-Roman JJ, et al. Clinicopathologic study and DNA analysis of 37 cardiac myxomas (A 28-year experience). Chest. 2003;123:1379–1385
  3. Butany J, Nair V, Naseemuddin A, et al. Cardiac tumours: diagnosis and management. Lancet Oncol. 2005;6:219–228
  4. Burke A, Virmani R. Tumors of the heart and great vessels, in Atlas of Tumor Pathology. In: Washington DC: Armed Forces Institute of Pathology; 1996;p. 1–98
  5. Uzun O, Wilson DG, Vujanic GM, et al. Cardiac tumours in children. Orphanet J Rare Dis. 2007;2:11
  6. Vasquez A, Sethi G, Maximov M, et al. Atrial myxomas in the elderly: a case report and review of the literature. Am J Geriatr Cardiol. 2004;13:39–44
  7. Sugeng L, Lang RM. Atypical cardiac myxomas. Echocardiography. 2004;21:43–47
  8. Sarjeant JM, Butany J, Cusimano RJ. Cancer of the heart (Epidemiology and management of primary tumors and metastases). Am J Cardiovasc Drugs. 2003;3:407–421
  9. Mittle S, Makayus AN, Boulis L, et al. Right-sided myxomas. J Am Soc Echocardiogr. 2005;18:695
  10. Chen MY, Wang J, Chao S, et al. Cardiac myxoma originating from the anterior mitral leaflet. Jpn Heart J. 2003;44:429–434
  11. Okamoto T, Doi H, Kazui T, et al. Aortic valve myxoma mimicking vegetation: report of a case. Surg Today. 2006;36:927–929
  12. Dandolu BR, Iyer KS, Das B, et al. Nonsyndromic familial atrial myxoma in two generations. J Thorac Cardiovasc Surg. 1995;110:872–874
  13. Carney JA, Hruska L, Beauschamp GD. Dominant inheritance of the complex of myxomas, spotty pigmentation and endocrine overactivity. Mayo Clin Proc. 1986;61:165–172
  14. Shaptro LM. Cardiac tumours: diagnosis and management. Heart. 2001;85:218–222
  15. McCarthy PM, Pichler JM, Schaff HV. The significane of multiple, recurrent, and “complex” cardiac myxomas. J Thorac Cardiovasc Surg. 1986;91:389–396
  16. Mabuchi T, Shimizu M, Ino H, et al. PRKAR1A gene mutation in patients with cardiac myxoma. Int J Cardiol. 2005;102:273–277
  17. Li Y, Pan Z, Ji Y, et al. Herpes simplex virus type 1 infection associated with atrial myxoma. Am J Pathol. 2003;163:2407–2412
  18. Acebo E, Val-Benal JF, Gomez-Roman JJ. Prichard’s structures of the fossa ovalis are not histogenetically related to cardiac myxoma. Histopathology. 2001;39:529–535
  19. Amano J, Kono T, Wada Y, et al. Cardiac myxoma: its origin and tumor characteristics. Ann Thorac Cardiovasc Surg. 2003;9:215–221
  20. Orlandi A, Ciucci A, Ferlosio A, et al. Cardiac myxoma cells exhibit embryonic endocardial stem cell features. J Pathol. 2006;209:231–239
  21. Swartz MF, Lutz CJ, Chandan VS, et al. Atrial myxomas: pathologic types, tumor location, and presenting symptoms. J Card Surg. 2006;21:435–440
  22. Sakamoto H, Sakamaki T, Kanda T, et al. Vascular endothelial growth factor is an autocrine growth factor for cardiac myxoma cells. Circ J. 2004;68:488–493
  23. Ibanez B, Marcos-Alberca P, Rey M, et al. Multicavitated left atrial myxoma mimicking a hydatid cyst. Eur J Echocardiogr. 2005;6:231–233
  24. Hemachandran M, Khakkar N, Khandelwal N. Giant-cell-rich myxoma of right atrium (An ultrstructural analysis). Cardiovasc Pathol. 2003;12:287–289
  25. Dubel HP, Knebel F, Gliech V, et al. Atypical vessels as an early sign of intracardiac myxoma?. Cardiovasc Ultrasound. 2004;2:13
  26. Chopra P, Ray R, Singh MK, et al. Cardaic myxoma with glandular elements: a histologic, histochemical and immunohistochemical evaluation. Indian Heart J. 2003;55:182–184
  27. Malekzadeh S, Roberts WC. Growth rate of left atrial myxoma. Am J Cardiol. 1989;64:1075–1076
  28. Grebene ML, Rosado-de-Christenson ML, Green CE, et al. Cardiac myxoma: imaging features in 83 patients. Radiographics. 2004;22:673–689
  29. Ekinci EI, Donnan GA. Neurological manifestations of cardiac myxoma: a review of literature and report of cases. Intern Med J. 2004;34:243–249
  30. Revankar SG, Clark RA. Infected cardiac myxoma: case report and literature review. Medicine. 1998;77:337–344
  31. Gowda RM, Khan IA, Nair CK, et al. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am Heart J. 2003;146:404–410
  32. Feingold RM. Cardiac valvular tumors: cardiac papillary fibroelastoma. J Insur Med. 2003;35:174–178
  33. Kurup AN, Tazelaar HD, Edwards WD, et al. Iatrogenic cardiac papillary fibroelastoma: a study of 12 cases (1990 to 2000). Hum Pathol. 2002;33:1165–1169
  34. Grandmougin D, Fayad G, Moukassa D, et al. Cardiac valve papillary fibroelastomas: clinical, histological and immunohistochemical studies and a physiopathogenic hypothesis. J Heart Valve Dis. 2000;9:832–841
  35. Eslami-Varzaneh F, Brun EA, Sears-Rogan P. An unusual case of multiple papillary fibroelastoma: review of literature. Cardiovasc Pathol. 2003;12:170–173
  36. Fayad G, Modine T, Le Tourneau T, et al. An unusual case of papillary fibroelastoma “invading” the mitral valve. J Thorac Cardiovasc Surg. 2006;132:1472–1473
  37. Kim HK, Kim YJ, Chang SA, et al. Cardiac papillary fibroelastoma manifested as a left ventricular cystic mass. Int J Cardiol. 2005;101:507–508
  38. Hort W, Horstkotte D. Fibroelastoma and Lambl’s excrescences: localization (Morphology and pathogenesis, differential diagnosis and infection). J Heart Valve Dis. 2006;15:591–593
  39. Dehnee AE, Brizendine S, Herrera CJ. Recurrent strokes in a young patient with papillary fibroelastoma: a case report and literature review. Echocardiography. 2006;23:592–595
  40. Koji T, Fujioka M, Imai H, et al. Infected papillary fibroelastoma attached to the atrial septum. Circ J. 2002;66:305–307
  41. Boodhwani M, Veinot JP, Hendry PJ. Surgical approach to cardiac papillary fibroelastomas. Can J Cardiol. 2007;23:301–302
  42. Maxey TS, Grow P, Morris CD, et al. Biatrial primary cardiac paraganglioma: a rare finding. Cardiovasc Pathol. 2007;16:179–182
  43. McGann C, Tazelaar H, Cho SR, et al. In vivo detection of encapsulated intracardaic paraganglioma by delayed gadolinium enchancement magnetic resonance imaging. J Cardiothorac Magn Reson. 2005;7:371–375
  44. Imren Y, Tasoglu I Benson AA, et al. A rare intracardiac mass: cardiac paraganglioma. Heart Lung Circ. 2007;16:116–117
  45. Early SA, McGuinness J, Galvin J, et al. Asymptomatic schwannoma of the heart. J Cardiothorac Surg. 2007;4:1
  46. Iino K, Matsumato Y, Endo M, et al. Surgical treatment of a left ventricular neurofibroma. J Card Surg. 2006;21:278–280

PII: S0740-2570(07)00101-3

doi: 10.1053/j.semdp.2007.10.005

Seminars in Diagnostic Pathology
Volume 25, Issue 1 , Pages 20-28 , February 2008

Article Tools

* Image Usage & Resolution