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Seminars in Diagnostic Pathology
Volume 23, Issue 2
, Pages 103-110
, May 2006
GIST: Particular aspects related to cell cultures, xenografts, and cytogenetics
References
- Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 1998;279:577–580
- Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med. 2001;344:1052–1056
- Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol. 2006;24:25–35
- . Biology of gastrointestinal stromal tumors. J Clin Oncol. 2004;22:3813–3825
- Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol. 1998;152:1259–1269
- Embryonic form of smooth muscle myosin heavy chain (SMemb/MHC-B) in gastrointestinal stromal tumor and interstitial cells of Cajal. Am J Pathol. 1999;154:23–28
- . Interstitial cells of Cajal: intestinal pacemaker cells?. Adv Anat Embryol Cell Biol. 1982;71:1–130
- Congenital interstitial cell of cajal hyperplasia with neuronal intestinal dysplasia. Am J Surg Pathol. 2000;24:1568–1572
- Developmental origin and Kit-dependent development of the interstitial cells of cajal in the mammalian small intestine. Dev Dyn. 1998;211:60–71
- . A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract. Gastroenterology. 1996;111:492–515
- Interstitial cells of Cajal generate a rhythmic pacemaker current. Nat Med. 1998;4:848–851
- . Gastrointestinal stromal tumor workshop. Hum Pathol. 2001;32:578–582
- Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase. Proc Natl Acad Sci U S A. 2003;100:6706–6711
- Induction of gastric GIST in rat and establishment of GIST cell line. Cancer Lett. 2006;231:295–303
- Gastrointestinal stromal tumours overexpress fatty acid synthase. J Pathol. 2006;209:369–375
- STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications. Oncogene. 2001;20:5054–5058
- Effects of imatinib vary with the types of KIT-mutation in gastrointestinal stromal tumor cell lines. Oncol Rep. 2005;14:645–650
- Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol. 2003;21:4342–4349
- PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib. J Clin Oncol. 2005;23:5357–5364
- Cellular uptake of the tyrosine kinase inhibitors imatinib and AMN107 in gastrointestinal stromal tumor cell lines. Pharmacology. 2006;77:11–16
- Value of nude mice xenografts in the expression of cell heterogeneity of human sarcomas of bone and soft tissue. Pathol Res Pract. 1988;183:683–692
- Tissue microarray profiling of primary and xenotransplanted synovial sarcomas demonstrates the immunophenotypic similarities existing between SYT-SSX fusion gene confirmed, biphasic and monophasic fibrous variants. Virchows Arch. 2006;449:435–437
- Structural basis of tumoral angiogenesis. Adv Exp Med Biol. 2003;532:69–89
- Conventional and molecular cytogenetic characterization of a new human cell line, GIST-T1, established from gastrointestinal stromal tumor. Lab Invest. 2002;82:663–665
- Establishment of a mouse gastrointestinal stromal tumour model and evaluation of response to imatinib by small animal positron emission tomography. Anticancer Res. 2006;26:1247–1252
- An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development. Cancer Res. 2005;65:9633–9636
- A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E. Cancer Res. 2005;65:6631–6639
- A novel gain of function mutant in C-kit gene and its tumorigenesis in nude mice. World J Gastroenterol. 2005;11:7104–7108
- Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: a study by the Spanish Group for Sarcoma Research (GEIS). J Clin Oncol. 2005;23:6190–6198
- Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors. J Clin Oncol. 2002;20:3898–3905
- DNA copy number losses in chromosome 14: an early change in gastrointestinal stromal tumors. Cancer Res. 1996;56:3230–3233
- DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance. Cancer Res. 2000;60:3899–3903
- Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: clinicopathologic and immunohistochemical study of 26 cases. Am J Surg Pathol. 1999;23:1109–1118
- Extragastrointestinal (soft tissue) stromal tumors: an analysis of 48 cases with emphasis on histologic predictors of outcome. Mod Pathol. 2000;13:577–585
- . Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: gastrointestinal stromal tumors. Cancer Genet Cytogenet. 2002;135:1–22
- Loss of 14q and 22q in gastrointestinal stromal tumors (pacemaker cell tumors). Cancer Genet Cytogenet. 2000;120:111–116
- High-resolution deletion mapping of chromosome 14 in stromal tumors of the gastrointestinal tract suggests two distinct tumor suppressor loci. Genes Chromosomes Cancer. 2000;27:387–391
- Gastrointestinal stromal tumor, uncommitted type, with monosomies 14 and 22 as the only chromosomal abnormalities. Cancer Genet Cytogenet. 1998;102:135–138
- Cytogenetic and morphologic characteristics of gastrointestinal stromal tumors (Recurrent rearrangement of chromosome 1 and losses of chromosomes 14 and 22 as common anomalies). Verh Dtsch Ges Pathol. 1998;82:275–278
- Two cases of low-grade gastric leiomyosarcoma with monosomy 14 as the only change. Cancer Genet Cytogenet. 1996;90:184–185
- Chromosomal aberrations in malignant gastrointestinal stromal tumors: correlation with c-KIT gene mutation. Cancer Genet Cytogenet. 2001;128:24–30
- Allelic loss of 14q and 22q, NF2 mutation, and genetic instability occur independently of c-kit mutation in gastrointestinal stromal tumor. Jpn J Cancer Res. 2000;91:1241–1249
- CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34. Mod Pathol. 1998;11:728–734
- Different patterns of DNA copy number changes in gastrointestinal stromal tumors, leiomyomas, and schwannomas. Hum Pathol. 1998;29:476–481
- Loss of heterozygosity at 1p36 predicts poor prognosis in gastrointestinal stromal/smooth muscle tumors. Lab Invest. 1999;79:1461–1467
- Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors. Genes Chromosomes Cancer. 1994;10:231–243
- High-resolution cDNA microarray CGH mapping of genomic imbalances in osteosarcoma using formalin-fixed paraffin-embedded tissue. Cytogenet Genome Res. 2004;107:77–82
- Comparative genomic hybridization study on pooled DNAs from tumors of one clinical-pathological entity. Cancer Genet Cytogenet. 1998;100:25–30
- Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nat Genet. 1999;23:41–46
- High resolution analysis of DNA copy number variation using compartaive genomic hybridization to microarrays. Nat Genet. 1998;20:207–211
- High-resolution global profiling of genomic alterations with long oligo-nucleotide microarray. Cancer Res. 2004;64:4744–4748
- High-resolution characterization of the pancreatic adenocarcinoma genome. Proc Natl Acad Sci U S A. 2004;101:9067–9072
- Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients. Hum Mol Genet. 2006;15:1015–1023
- . Clinicopathologic correlations in gastrointestinal stromal tumors. Hum Pathol. 2002;33:455
- Biological and clinical significance of cytogenetic abnormalities in low-risk and high-risk gastrointestinal stromal tumors. Hum Pathol. 2002;33:316–321
- Putative chromosomal deletions on 9P, 9Q and 22Q occur preferentially in malignant gastrointestinal stromal tumors. Int J Cancer. 2000;85:633–638
- Loss of heterozigosity of chromosome 9p and loss of p16INK4A expression are associated with malignant gastrointestinal stromal tumor. Mod Pathol. 2004;17:1364–1371
- 9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor alpha gene alterations. Cancer. 2005;104:159–169
- . A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature. 1993;366:704–707
- . The INK4/ARF locus and its two gene products. Curr Opin Genet Dev. 1999;9:22–30
- . Cancer cell cycles. Science. 1996;274:1672–1677
- Role of p16/INK4a in gastrointestinal stromal tumor progression. Am J Clin Pathol. 2004;122:35–43
- High prognostic value of p16INK4A alterations in gastrointestinal stromal tumors. J Clin Oncol. 2003;21:1688–1697
- Chromosomal numerical abnormality profiles of gastrointestinal stromal tumors. Jpn J Clin Oncol. 2006;36:85–92
- Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants. Gastroenterology. 2005;128:270–279
- Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. Clin Cancer Res. 2005;11:4182–4190
PII: S0740-2570(06)00140-7
doi: 10.1053/j.semdp.2006.08.004
© 2006 Elsevier Inc. All rights reserved.
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Seminars in Diagnostic Pathology
Volume 23, Issue 2
, Pages 103-110
, May 2006
