Seminars in Diagnostic Pathology
Volume 23, Issue 1 , Pages 56-60 , February 2006

The pathogenesis of mesothelioma

  • Michele Carbone, MD, PhD

      Affiliations

    • Thoracic Oncology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii
    • Corresponding Author InformationAddress reprint requests and correspondence: Michele Carbone, MD, PhD, Cancer Research Center of Hawaii, 651 Ilalo St., BSB Room 228, Honolulu, HI 96813.
    • ,
  • Carlos W.M. Bedrossian, MD, PhD (Hon), FIAC

      Affiliations

    • Department of Pathology, Norwegian American Hospital, Chicago, Illinois.

References 

  1. Carbone M , Kratzke R , Testa JR . The pathogenesis of mesothelioma . Semin Oncol . 2002;29:2–17
  2. Sluis-Kremer GK . Asbestos disease at low exposures after long residence times . Ann NY Acad Sci . 1991;643:182–193
  3. Saffiotti U . Mesothelioma carcinogenesis: in vivo models . In:  Pass HI ,  Vogelzang NJ ,  Carbone M editor. Malignant Mesothelioma . New York, NY: Springer; 2005;p. 60–86
  4. Ramos Nino ME , Testa JR , Altomare DA , et al.   Cellular and molecular parameters of mesothelioma . J Cell Biochem . 2006;98:723–734
  5. Kagan E . Immune status and mesothelioma . In:  Pass HI ,  Vogelzang NJ ,  Carbone M editor. Malignant Mesothelioma . New York, NY: Springer; 2005;p. 151–165
  6. Bocchetta M , Di Resta I , Powers A , et al.   Human mesothelial cells are unusually susceptible to SV40 mediated transformation and asbestos carcinogenicity . Proc Natl Acad Sci USA . 2000;97:10214–10219
  7. Yang H , Bocchetta M , Krocznyska B , et al.   TNF-α inhibits asbestos-induced cytotoxicity via a NF-κB dependent pathway, a possible mechanism for asbestos-induced oncogenesis . Proc Natl Acad Sci USA . 2006;103:10397–10402
  8. Powers A , Carbone M . The role of environmental carcinogens, viruses, and genetic predisposition in the pathogenesis of mesothelioma . Cancer Biol Ther . 2002;1:350–355
  9. McDonald JC , McDonald A . Mesothelioma and asbestos exposure . In:  Pass HI ,  Vogelzang NJ ,  Carbone M editor. Malignant Mesothelioma . New York, NY: Springer; 2005;p. 267–292
  10. Smith AH , Wright CC . Chrysotile asbestos is the main cause of pleural mesothelioma . Am J Ind Med . 1996;30:252–266
  11. Dogan UA , Baris IY , Dogan M , et al.   Genetic predisposition to fiber carcinogenesis causes a mesothelioma epidemic in Turkey . Cancer Res . 2006;66:5063–5068
  12. Carbone M , Rdzanek MA , Rudzinski JJ , et al.   Cancer Res . 2005;65:10120–10121
  13. Cutrone R , Lednicky J , Dunn G , et al.   Some oral poliovirus vaccines were contaminated with infectious SV40 after 1961 . Cancer Res . 2005;65:10273–10279
  14. Gazdar A , Butel JS , Carbone M . SV40 and human tumors: myth, association or causality? . Nat Rev Cancer . 2002;2:957–964
  15. Carbone M , Klein G , Gruber J , et al.   Modern criteria to establish human cancer etiology . Cancer Res . 2004;64:5518–5524
  16. Kroczynska B , Cutrone R , Bocchetta M , et al.   Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters . Proc Natl Acad Sci USA . 2006;103:14128–14133

PII: S0740-2570(06)00136-5

doi: 10.1053/j.semdp.2006.08.002

Seminars in Diagnostic Pathology
Volume 23, Issue 1 , Pages 56-60 , February 2006

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